Open Journal Systems

The Clinical Application of Magnetic Resonance Imaging and Double Spiral Computed Tomography in the Diagnosis of Bone Tumor

Adam R Botha (epartment of Radiation Oncology, Faculty of Medicine, University of Cape Town, Cape Town, South Africa)
Zhihui Liu (Department of Research, Rajiv Gandhi Cancer Institute & Research Centre, Delhi, India)


The purpose of the study was to observe the diagnostic effect and clinical application value of magnetic resonance imaging (MRI) and double spiral computed tomography (CT) in tumor diagnosis. A total of 68 patients with genu bone tumor were selected, including 48 patients in group A and 56 patients in group B. The 36 patients in group C, who received combined treatment. After comparison of the clinical diagnosis results of the three detection methods, it was found that the detection rate of knee bone tumor was 72.92% in group A and 83.93% in group B, with no statistically significant difference (P>0.05). The detection rate of tumor lesions in group C was 97.22%, significantly higher than that in group A and B. The detection rate of patients in group A, B and C showed an increasing trend, and the difference between group C and Group A and B was significant (P<0.05). Therefore, MRI and double spiral CT had similar detection rates in the diagnosis of knee bone tumors, but double spiral CT can better display the lesion scope and the fine structure of bone tumors. MRI detection had obvious advantages in the diagnosis of the range of bone tumors, such as soft tissue masses and bone marrow edema.


Magnetic resonance imaging; Double spiral computed tomography; The joint detection

Full Text:



Gould C F , Ly J Q , Jr G E L , et al. Bone Tumor Mimics: Avoiding Misdiagnosis[J]. Curr Probl Diagn Radiol, 2007, 36(3):124-141.

Schinhan M , Tiefenboeck T , Funovics P , et al. Extendible Prostheses for Children After Resection of Primary Malignant Bone Tumor: Twenty-seven Years of Experience[J]. Journal of Bone & Joint Surgery American Volume, 2015.

Bergovec M , Dubravko Orlić, Korpar J , et al. Bone tumor incidence in patients treated operatively in the Department of Orthopaedic Surgery Clinical Hospital Centre Zagreb, from 1981 to 2006[J]. Experimental Neurology, 2008, 166(2):254-265.

Xu Z, Hurchla MA, Deng H, et al. Interferon-gamma, osteoclast, bone metastases, hypercalcemia of malignancy[J]. Journal of Biological Chemistry, 2009, 284(7):4658-66.

Schajowicz F . Tumors and Tumor-Like Lesions of Bone[J]. Skeletal Radiology, 2010, 25(6):593-593.

Rui, Jiang, Ziyan, et al. Research Progress of Bone Tumor Clinical Diagnosis[C], 2018.

Cervio L I, Du J , Jiang S B . MRI-guided tumor tracking in lung cancer radiotherapy[J]. Physics in Medicine & Biology, 2011, 56(13).

Prasad S R , Jhaveri K S , Sanjay S , et al. CT tumor measurement for therapeutic response assessment: comparison of unidimensional, bidimensional, and volumetric techniques initial observations.[J]. Radiology, 2002, 225(2):416.

Huang R , Han L , Li J , et al. Chlorotoxin-modified macromolecular contrast agent for MRI tumor diagnosis[J]. Biomaterials, 2011, 32(22):5177-5186.

H. E. Daldrup-Link, D. Golovko, B. Ruffell, et al. MRI of Tumor-Associated Macrophages with Clinically Applicable Iron Oxide Nanoparticles[J]. Clinical Cancer Research, 2011.

Lauenstein T C , Salman K , Morreira R , et al. Gadolinium-enhanced MRI for tumor surveillance before liver transplantation: center-based experience.[J]. Ajr American Journal of Roentgenology, 2007, 189(3):663-70.

Ketelsen D , Horger M , Buchgeister M , et al. Estimation of Radiation Exposure of 128-Slice 4D-Perfusion CT for the Assessment of Tumor Vascularity[J]. Korean Journal of Radiology Official Journal of the Korean Radiological Society, 2010, 11(5).

Sahani D V , Holalkere N S , Mueller P R , et al. Advanced hepatocellular carcinoma: CT perfusion of liver and tumor tissue--initial experience.[J]. Radiology, 2007, 243(3):736.

Shen S H , Wang J H , Chen K K , et al. Retroperitoneal glomus tumor: CT and MRI appearance[J]. European Journal of Radiology Extra, 2011, 77(3):79-83.

Zhang Haidong, Wang Renfa, Song Shaohui, et al. CT and MRI diagnosis of primary chondrosarcoma of the spine. Chinese Journal of Clinical Medical Imaging, 2010, 21(1):24-27.



  • There are currently no refbacks.

Copyright (c) 2020 Adam R Botha, Zhihui Liu

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.