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Diagnostic Value of Quantitative Parameters of DCE-MRI in Endometrial Carcinoma and Its Correlation with Clinicopathological Factors

Xinyi Fang (Central Hospital of Fengcheng City,Dandong City,Liaoning Province,China)


In the study, 108 patients with endometrial cancer were selected as the observation group, and 105 patients with benign endometrial lesions were selected as the control group. After DCE-MRI examination, it was found that the volume transfer constant (Ktrans), rate constant (Ke) and extracellular space volume ratio (Ve) in the observation group were higher than those in the control group (P < 0.05). The area under curve (AUC) of combined Ktrans, Ke and Ve values in the diagnosis of endometrial cancer was 0.841. The values of Ktrans, Ke and Ve were positively correlated with the clinical stage and the degree of muscular invasion, but negatively correlated with the degree of differentiation (P < 0.05). The results of the study suggested that DCE-MRI quantitative parameters have a certain value in the differential diagnosis of endometrial cancer, which helped to further distinguish the degree of muscular invasion, clinical stage, and differentiation of endometrial cancer patients. 


dynamic contrast enhanced magnetic resonance imaging; volume transfer constant rate constant; extravascular extra-cellular space volume ratio; endometrial cancer; clinicopathological factors

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