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Primary diffuse large B-cell lymphoma of endometrium

Yuqing Zou ()
Hongmin Zhao ()
Jianhua Gao ()
Hong Zhu ()
Yong Li ()
Jianhua Zheng ()


This article was designed to analyze the prognosis and to explore the clinical characteristics and treatment of a case of primary diffuse large B-cell lymphoma (DLBCL) of the endometrium, through a detailed report. Methods: This report was done by analyzing a case through its clinical features, pathological examination and immunophenotyping. We believe that this would allow us to forecast the prognosis of the case. Case Description: The patient was admitted because of irregular postmenopausal vaginal bleeding for more than a month. She underwent a series of surgical procedures that included abdominal hysterectomy, bilateral adnexectomy, pelvic lymph node dissection and enterolysis owing to the assessed pathological results after uterine curettage. The postoperative pathological results showed that it was a DLBCL. Conclusion: Primary DLBCL of the endometrium is rarely reported. Its diagnosis and differential diagnosis mainly depends on pathological examination and immunophenotyping. Radical surgery combined with chemotherapy may be an ideal mode of treatment. The prognosis of the disease has a varied range but radical surgery combined with chemotherapy may improve her quality of life and prolong her survival period.


endometrial cancer; diffuse large B cell lymphoma; non Hodgkin lymphoma (NHL)

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