A Royal Jelly Mixture with Berberine for Dressing Change on a Refractory Skin Ulcer: A Case Report

Weisheng He (No.2 Department of Geriatrics, Hangzhou Wenzhong Hospital, Hangzhou, 310000, China)
Mimi Zhou (No.2 Department of Geriatrics, Hangzhou Wenzhong Hospital, Hangzhou, 310000, China)
Yue Chen (No.2 Department of Geriatrics, Hangzhou Wenzhong Hospital, Hangzhou, 310000, China)


It has been reported that a 92-year-old female had got a bruise superficialwound on her right leg one and a half years ago, developing into refractoryskin ulcer due to improper management before. A prepared cream, mixedroyal jelly with berberine for dressing change, was made on the scenethrough the crush of berberine tablets, working with fresh royal jelly.Topical dressing change with the cream was done every 3 days, and twomonths later, such the ulcer became clean and was covered fully with freshgranulation tissue. This kind of cream consists of the ingredients of TCMpurely, free of antibiotic, and being quite effective clinically, also helpfulfor proper use of antibiotic.


Refractory skin ulcer;A mixture of TCM dressing change;Proper use of antibiotic

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DOI: https://doi.org/10.30564/jgm.v3i2.3472


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